St. Giles is a historic home located at Hebron, Wicomico County, Maryland, United States. It is a -story frame Federal period farmhouse, with a 20th-century hyphen and wing. Also on the property are several outbuildings, including a well house, wood house, tenant house, barn, garage, and pool house. The landscaped grounds include a garden which is thought to retain its original early-19th-century layout.
St. Giles was listed on the National Register of Historic Places in 1982.