The St. Francis Pro-Cathedral or simply Church of St. Francis, is a Roman Catholic church located in the city of Tripoli, Libya.
The St. Francis Pro-Cathedral serves as a parish church and the pro-cathedral or temporary cathedral of the Latin Church Apostolic Vicariate of Tripoli (Vicariatus Apostolicus Tripolitanus) which was created in 1630 by Pope Urban VIII.
It is located approximately from the former Tripoli Cathedral, completed in 1928, which was converted into a mosque in . The pro-cathedral is run by the Franciscans of the Province of St. Paul the Apostle (Malta) with the church of Mary Immaculate in Benghazi.