The St. Dominic Co-Cathedral (also known as Moquegua Cathedral; ), is the main Catholic church in the city of Moquegua in Peru. It is a property of the Catholic Church. It is located in the .
It is a co-cathedral that follows the Roman or Latin rite and is one of the two co-cathedrals owned by the Diocese of Tacna and Moquegua () that was created in 1944 by Pope Pius XII through the bull .
It is under the pastoral responsibility of Bishop .