St. Brendan's is a town in the Canadian province of Newfoundland and Labrador, situated in Shoal Cove (the town's former name) on Cottel Island in Bonavista Bay. Other settlements on the island include Shalloway Cove, Haywards Cove, and Dock Cove. The town had a population of 125 in the Canada 2021 Census. St. Brendan's is inaccessible by road and is served by a daily ferry service from Burnside.
St. Gabriel's All Grade is the only school in the community and in 2018 had only six students.
In the 2021 Census of Population conducted by Statistics Canada, St. Brendan's had a population of living in of its total private dwellings, a change of from its 2016 population of . With a land area of , it had a population density of in 2021.