Spokane is an unincorporated community and census-designated place (CDP) in Concordia Parish, Louisiana, United States. As of the 2020 census, Spokane had a population of 378.
It is located in northeastern Concordia Parish on the southwest side of Lake St. John, an oxbow lake that is a former channel of the Mississippi River. Louisiana State Highway 568 leads southwest from Spokane to Ferriday.
Spokane was first listed as a census designated place in the 2010 U.S. census.