The Spanish missions in Mexico are a series of religious outposts established by Spanish Catholic Franciscans, Jesuits, Augustinians, and Dominicans to spread the Christian doctrine among the local natives. Since 1493, the Kingdom of Spain had maintained a number of missions throughout Nueva España (New Spain, consisting of what is today Mexico, the Southwestern United States, the Florida and the Luisiana, Central America, the Spanish Caribbean and the Philippines) in order to preach the gospel to these lands. In 1533, at the request of Hernán Cortés, Carlos V sent the first Franciscan friars with orders to establish a series of installations throughout the country.
Topia, the western province of Nueva Vizcaya, contained three major missions: Xiximes, San Andrés, and Santa Cruz de Topia. These were each subdivided into several districts, or , each of which in turn contained several pueblos, or .
First district:
Second district:
Third district:
Fourth district:
First district:
Second district:
Third district:
Fourth district:
First district:
Second district:
Third district:
Parras, the eastern province of Nueva Vizcaya, contained six major missions with their , as follows.
Mission San Pablo Tepehuanes had the following and :
First district:
Second district:
Third district:
Fourth district:
Other missions in Nueva Vizcaya included: