The Southern Six Conference is a former high school athletic conference in Wisconsin, consisting of schools in the state's south central region. It was in operation from 1928 to 1941 and all members were part of the Wisconsin Interscholastic Athletic Association.
The Southern Six Conference, also known as the Southern Wisconsin Six in its early years, was formed in 1928 by six medium-sized high schools in south central Wisconsin: Edgerton, Fort Atkinson, Monroe, Stoughton, Watertown and the University of Wisconsin High School (Wisconsin High). Three conference members (Edgerton, Fort Atkinson and Stoughton) formerly belonged to the Rock River Valley League, Monroe entered the conference from the Southwest Wisconsin Athletic League, and Watertown was previously a member of the Little Ten Conference but left to seek out stronger competition in athletics. The conference lasted for thirteen years before Watertown was forced out by the five other conference members, and the conference was dissolved in 1941. The remaining schools, along with five schools who left the South Central Conference for similar reasons (Baraboo, Portage, Reedsburg, Richland Center and Wisconsin Dells) went on to form the Southern Ten Conference, which competed for eleven years before its dissolution in 1952.
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