South Spencer High School is a public high school in Reo, Indiana. The school educates about 352 students in grades 9 to 12 in the South Spencer School Corporation district.
The school formed in 1965 by the merger of Luce Township High School and Rockport High School.
The school's athletic nickname is the "Rebels", and it participates in the Pocket Athletic Conference.
In 2007, 2011, 2013, & 2015 the boys' baseball team won the Division 2A State Title.
The mascot of South Spencer is the Rebel Man.