South Carolina Highway 83 (SC 83) is a primary state highway in the U.S. state of South Carolina. It connects the communities of eastern Marlboro County with Maxton, North Carolina.
SC 83 is a two-lane rural highway that traverses from a point northeast of Clio at SC 381 to the North Carolina state line where the road continues as North Carolina Highway 83 (NC 83).
The highway was established in 1938 as a renumbering of SC 68 to match NC 83; no changes have been made since.