South Africa sent a team to compete at the 2008 Summer Paralympics in Beijing, China and finished 6th on the medal table.
Natalie du Toit, five time gold medallist at the Athens Paralympics in 2004, competed in six swimming events. She also represented South Africa at the Beijing Olympics. Other members of the swim team included Charl Bouwer, Kevin Paul, Tadgh Slattery, Achmat Hassiem, Shireen Sapiro, Emily Gray, Sarah Shannon, Adri Visser and Beth Nothling. South Africa also sent a swimming official, Sharief Gamiet, to the games.
Oscar Pistorius represented South Africa in athletics.
South African representatives also competed in wheelchair basketball.
The following South African athletes won medals at the games:
* Indicated the three best individual scores that count towards the team total.
Group A Matches
Classification 9-12
Ninth place