James Columbus Reese, also called "Lefty" and "Sleeky", (December 21, 1912 – March 31, 1978) was an American baseball pitcher in the Negro leagues. He played with the Cleveland Red Sox in 1934, the Brooklyn Eagles in 1935, the Atlanta Black Crackers from 1937 to 1938 and the Baltimore Elite Giants in 1940.
He graduated from Morris Brown College and later served as a school principal.