Skinners Run is a long second-order tributary to Marshyhope Creek in Dorchester County, Maryland. This is the only stream of this name in the United States.
Skinners Run rises about west of Federalsburg, Maryland and then flows southeast to join Marshyhope Creek about southwest of Federalsburg, Maryland.
Skinners Run drains of area, receives about 44.5 in/year of precipitation, and is about 8.34% forested.