Skerne and Wansford is a civil parish in the East Riding of Yorkshire, England. It is situated approximately south-east of the town of Driffield and covering an area of .
The civil parish is formed by the villages of Skerne and Wansford.
According to the 2011 UK census, Skerne and Wansford parish had a population of 345, an increase on the 2001 UK census figure of 318.