Sisikon is a municipality in the canton of Uri in Switzerland. It is situated on the shore of Lake Lucerne.
Sisikon has an area, , of . Of this area, 30.9% is used for agricultural purposes, while 44% is forested. Of the rest of the land, 1.2% is settled (buildings or roads) and the remainder (23.8%) is non-productive (rivers, glaciers or mountains). , 36.5% of the total land area was heavily forested, while 4.1% is covered in small trees and shrubbery. Of the agricultural land, 0.2% is used for farming or pastures, while 4.5% is used for orchards or vine crops and 26.3% is used for alpine pastures. Of the settled areas, 0.4% is covered with buildings, 0.2% is listed as parks and greenbelts and 0.6% is transportation infrastructure. Of the unproductive areas, 0.4% is unproductive standing water (ponds or lakes), 0.2% is unproductive flowing water (rivers), 7.7% is too rocky for vegetation, and 15.5% is other unproductive land.
Spilauersee is located on an alp below Rossstock.
Sisikon has a population (as of ) of . , 6.8% of the population was made up of foreign nationals. Over the last 10 years the population has decreased at a rate of -2.8%. Most of the population () speaks German (96.0%), with Italian being second most common (1.4%) and Serbo-Croatian being third (1.1%). the gender distribution of the population was 51.8% male and 48.2% female.
In the 2007 federal election the FDP party received 75% of the vote.
In Sisikon about 69.7% of the population (between age 25-64) have completed either non-mandatory upper secondary education or additional higher education (either university or a Fachhochschule).
Sisikon has an unemployment rate of 0.36%. , there were 24 people employed in the primary economic sector and about 12 businesses involved in this sector. 11 people are employed in the secondary sector and there are 4 businesses in this sector. 90 people are employed in the tertiary sector, with 16 businesses in this sector.
The historical population is given in the following table:
Sisikon is served by the Sisikon station, situated within the municipality and on the Gotthard railway. Sisikon can be accessed by road via the Axenstrasse.