Siracusaville is a census-designated place (CDP) in St. Mary Parish, Louisiana, United States. As of the 2020 census, Siracusaville had a population of 297. It is part of the Morgan City Micropolitan Statistical Area.
Siracusaville is located at (29.68715, -91.14186), adjacent to the eastern border of Morgan City. Louisiana State Route 182 is an east-west road that passes through the southern part of the community, along the edge of Bayou Boeuf, part of the Intracoastal Waterway. U.S. Route 90, a four-lane expressway, forms the northeastern border of the CDP but provides no direct access to it; the closest exits are Exit 176 in Morgan City to the west and Exit 181 in Amelia to the east.
According to the United States Census Bureau, the CDP has a total area of , of which is land and , or 6.37%, is water.
Siracusaville first appeared as a census designated place in the 2010 U.S. census.