Silene akaisialpina is a species of plant native to the mountains of central Honshu, Japan . It has also been reported on the island of Hokkaido.
In 1955, it was recognized by Takasi Yamazaki as a variety of Silene keiskei, called Melandrium keiskei var. akaisialpinum. It was later renamed Silene keiskei var. akaisialpina and then reclassified as its own species in 1997.