Sierra Leone competed at the 2022 Commonwealth Games held in Birmingham, England. This was Sierra Leone's 13th appearance at the Commonwealth Games.
Joshua Wyse and Hafsatu Kamara served as the country's opening ceremony flagbearers.
The following is the list of number of competitors participating at the Games per sport/discipline.
A squad of two judoka was entered as of 7 July 2022.
Sierra Leone was awarded a bipartite quota in the men's C3âÂÂ5 event in para-table tennis.