Sierra La Mojonera Flora and Fauna Protection Area is a protected natural area of northeastern Mexico. It covers a portion of the Sierra La Mojonera range, a western outlier of the Sierra Madre Oriental, in northern San Luis PotosÃÂ. The protected area was established in 2000, and covers an area of .
According to the National Biodiversity Information System of Comisión Nacional para el Conocimiento y Uso de la Biodiversidad (CONABIO) in Sierra La Mojonera Flora and Fauna Protection Area there are over 30 plant and animal species, of which 1 is exotic.