Shanghai No. 2 High School () is a public secondary school located in Shanghai, China.
Founded in 1902 by Wu Xin as Wu Pen Girls' School (), Shanghai No.2 High School holds the distinction of being the first independent girls' school established by Chinese nationals in the 20th century.
In 1947, the school relocated to 200 Yongkang Road (formerly 209 Route Remi), occupying the former campus of Ecole Primaire Russe (ä¿ÂÃ¥ÂÂÃ¥ÂÂç´Âå°Âå¸), which was later renamed and known as Ecole Municipale Française-Ecole Rémy (æ³ÂÃ¥ÂÂé·米å°Âå¸).
In 1952, Wu Pen Girls' School was renamed Shanghai No. 2 Girls' High School. In September 1967, the institution transitioned into a co-educational public school and was renamed Shanghai No. 2 High School.