Shahrisabz District () is a district of Qashqadaryo Region in Uzbekistan. The capital lies at the city Shahrisabz, itself not part of the district. It has an area of and its population is 223,800 (2021 est.). The district consists of 13 urban-type settlements (Miroqi, Qumqishloq, Oûrtaqoûrgûon, Chorshanbe, Temirchi, Yangiqishloq, Qutchi, Shamaton, Ammogûon-1, Qoûshqanot, Anday, Xoûjaxuroson, Keldihayot) and 12 rural communities.