Shadowrun is a pen and paper role-playing game, first released in 1989.
Shadowrun may also refer to:
- Video games based on the role-playing game:
- Shadowrun (1993 video game), a 1993 video game for the Super NES
- Shadowrun (1994 video game), a 1994 video game for the Sega Genesis
- Shadowrun (1996 video game), a 1996 video game for the Sega Mega-CD
- Shadowrun (2007 video game), a 2007 game for the Xbox 360 and Windows Vista
- Shadowrun Returns, a 2013 game for Windows, OS X and Linux, iOS and Android
- ', a 2014 game for Windows, OS X, Linux, iOS and Android
- ', a 2015 game for Linux, Windows, OS X, Android, iOS and Ouya
- ', a 2015 game for Windows, OS X, Linux
- ', a 1997 collectible card game
- Shadowrun Duels, a 2003 collectible miniatures game
- Other uses:
- Shadow Run (film), a 1998 crime film based on the novel The Shadow Run