Serhiy Shestakov (; born 12 April 1990) is a Ukrainian professional footballer who plays as a midfielder for Kolos-2 Kovalivka .
He played for the Ukrainian amateur football clubs, and then Shestakov spent time with some Ukrainian teams that played in the Ukrainian First League. But in July 2015 he signed a contract with the Ukrainian Premier League club FC Olimpik Donetsk. He made his debut for FC Olimpik as a substituted player in the game against FC Chornomorets Odesa on 18 July 2015 in the Ukrainian Premier League.
He is a twin brother of another Ukrainian football player, Mykhaylo Shestakov.