Sergio Zanetti (born 22 November 1967) is an Argentine football manager and former player who played as a defender.
He played for Talleres de Remedios de Escalada, Deportivo Español and Racing Club in Argentina, Cremonese (Italy), Verbania Calcio (Italy), AC Bellinzona (Switzerland) and FC Locarno (Switzerland).
After retirement he turned into a youth team coach (Allievi Nazionali level) for Lombardian clubs such as Pro Sesto, Monza and Como.
Zanetti is the older brother of former Inter and Argentina footballer Javier Zanetti.