Seren del Grappa is a comune (municipality) in the province of Belluno in the Italian region of Veneto, located about northwest of Venice and about southwest of Belluno. As of 31 December 2004, it had a population of 2,586 and an area of .
Seren del Grappa borders the municipalities of Arsiè, Feltre, Fonzaso, Pieve del Grappa, Setteville, and Valbrenta.