Segezhsky District (; ) is an administrative district (raion), one of the fifteen in the Republic of Karelia, Russia. It is located in the east of the republic. The area of the district is . Its administrative center is the town of Segezha. As of the 2010 Census, the total population of the district was 41,215, with the population of Segezha accounting for 71.9% of that number.
Within the framework of administrative divisions, Segezhsky District is one of the fifteen in the Republic of Karelia and has administrative jurisdiction over one town (Segezha), one urban-type settlement (Nadvoitsy), and thirty-four rural localities. As a municipal division, the district is incorporated as Segezhsky Municipal District. The town, the urban-type settlement, and six rural localities are incorporated into two urban settlements, while the remaining twenty-eight rural localities are incorporated into four rural settlements within the municipal district. The town of Segezha serves as the administrative center of both the administrative and municipal district.