Seed Cane Creek is a long 2nd order tributary to the Ararat River in Surry County, North Carolina.
Seed Cane Creek rises in Sheltontown, North Carolina and then flows southwest to join the Ararat River at Mount Airy.
Seed Cane Creek drains of area, receives about 47.5 in/year of precipitation, has a wetness index of 351.11, and is about 46% forested.