Sedeh Rural District () is in Sedeh District of Qaen County, South Khorasan province, Iran. It is administered from the city of Arianshahr.
At the time of the 2006 National Census, the rural district's population was 3,569 in 1,250 households. There were 3,264 inhabitants in 1,228 households at the following census of 2011. The 2016 census measured the population of the rural district as 3,180 in 1,220 households. The most populous of its 36 villages was Rum, with 567 people.