The Second Palaszczuk Ministry was a ministry of the Government of Queensland led by Annastacia Palaszczuk. Palaszczuk led the Labor Party to a majority victory in the 2017 state election.
On 11 December 2017, Premier Palaszczuk announced a new line up for the ministry. The ministry was sworn in by then-Governor Paul de Jersey on 12 December 2017. It was made up of nine men and nine women.
In May 2020, a minor reshuffle occurred following the resignation of Deputy Premier Jackie Trad. Health Minister Steven Miles was appointed Deputy Premier of Queensland, while Cameron Dick was appointed Treasurer of Queensland.