Sean Palfrey (born 24 July 1968) is a Welsh former professional darts player who played in Professional Darts Corporation (PDC) events.
Palfrey was a regular in the British Darts Organisation (BDO) World Professional Darts Championship, where his best result was reaching the quarter-finals in 1998. He played for the Welsh men's team in the WDF World Cup darts competition in 1997. He made a total of 32 international appearances for Wales.