Schizolaena manomboensis is a tree in the family Sarcolaenaceae. It is endemic to Madagascar. The specific epithet refers to Manombo Special Reserve where the species is found.
Schizolaena manomboensis grows as a large tree up to tall with a trunk diameter of up to . Its coriaceous leaves are elliptic to ovate in shape and are coloured brown above and orangish brown below. They measure up to long. The inflorescences have numerous flowers, each with three sepals and five petals. The round fruits measure up to in diameter and are partially hidden by the involucre. The wood is locally used in construction.
Schizolaena manomboensis is known only from the eastern coastal regions of Atsinanana and Atsimo-Atsinanana. Its habitat is humid forest from sea level to altitude. In Atsimo-Atsinanana, the species occurs in Manombo Reserve where forest is in a less degraded state than nearby areas.
Schizolaena manomboensis has been assessed as endangered on the IUCN Red List. Its habitat is threatened by deforestation and by agriculture, subsistence harvesting and wildfires. The species' presence in Manombo Special Reserve affords that subpopulation some protection.