El-Sayed Mohammed Nosseir (, August 31, 1905 – November 28, 1974) was an Egyptian weightlifter. Nosseir won the gold medal in the light heavyweight class at the 1928 Summer Olympics in Amsterdam. He set a new world record in both snatch with 112.5 kilograms and in the total of the three lifts with 355 kilograms, winning Egypt's first Olympic gold medal. Nosseir is the first African to win an Olympic gold medal in the history of the Olympic Games.