Santo Stefano al Mare () is a comune (municipality) in the Province of Imperia in the Italian region Liguria, located about southwest of Genoa and about southwest of Imperia. As of 31 December 2004, it had a population of 2,260 and an area of .
Santo Stefano al Mare borders the following municipalities: Cipressa, Pompeiana, Riva Ligure, and Terzorio.
The town can be found on the Riviera of Ponente, at around from the chief town of Genova. Its strategic placement helps to maintain a mild climate throughout the year, with temperatures rarely reaching the 0ð in winter and overcoming the 30ð in summer.