The Chapel of Saint Dominic Soriano () is a Roman Catholic church building in Villa Soriano, Soriano Department, Uruguay.
Santo Domingo Soriano was one of the oldest European settlements in the colonial Banda Oriental, dating to 1624. At that time it had a small chapel. The present building was constructed much later, but nevertheless constitutes a historic landmark. It features the only articulated image of Jesus Christ in Uruguay.
This chapel is annexed to the Parish of Dolores.