Santiago Sanz

Santiago Sanz may refer to:

• Santiago Sanz Fraile (1914-1980), known as Yayo, Spanish football midfielder turned manager
• Santiago Sanz Méndez (born 1962), known as Quecho, Spanish football midfielder
• Santiago Sanz (rugby union) (born 1979), Argentine rugby union player
• Santiago Sanz (parathlete) (born 1980), Spanish parathlete