Santiago Nathaniel Ryce Samaniego (born January 25, 1974) is a Panamanian former boxer who competed from 1993 to 2007, with a comeback in 2011.
Samaniego is a first cousin of Roberto Durán.
Nicknamed "El Herrero", Samaniego turned pro in 1993 and in 1997 took on undefeated Mihai Leu for the vacant WBO Welterweight title, but lost a decision. In 2002 he faced Mamadou Thiam for the interim WBA Light Middleweight Title, and won in a 12th round stoppage. In 2003, he was TKO'd by Alejandro GarcÃÂa, losing the belt. Since the loss, he dropped fights to Rhoshii Wells and Sechew Powell.