Sant'Onofrio (Calabrian: ) is a comune (municipality) in the Province of Vibo Valentia in the Italian region Calabria, located about southwest of Catanzaro and about northeast of Vibo Valentia. As of 31 December 2004, it had a population of 3,202 and an area of . It is named after Saint Onuphrius.
Sant'Onofrio borders the following municipalities: Filogaso, Maierato, Pizzo, Stefanaconi, Vazzano, Vibo Valentia.
The most common names in Sant'Onofrio.