Sant'Antonio di Gallura (Gallurese: Sant' Antòni, ) is a municipality in the Province of Gallura North-East Sardinia in the Italian region Sardinia, located about north of Cagliari and about northwest of Olbia. Sant'Antonio di Gallura borders the following municipalities: Arzachena, Calangianus, Luras, Olbia, Telti.
The economy is based on agriculture, animal husbandry and production of cork. People move seasonally to the nearby Arzachena and Olbia to work in touristic structures.