Sant'Anna d'Alfaedo is a comune (municipality) in the Province of Verona in the Italian region Veneto, located about west of Venice and about north of Verona. As of 31 December 2004, it had a population of 2,544 and an area of .
The municipality of Sant'Anna d'Alfaedo contains the frazioni (subdivisions, mainly villages and hamlets) Ronconi, Fosse, Giare, Cerna, Sant'Anna, and Ceredo.
Sant'Anna d'Alfaedo borders the following municipalities: Ala, Avio, Dolcè, Erbezzo, Fumane, Grezzana, Marano di Valpolicella, and Negrar.