Sant'Angelo di Piove di Sacco is a comune (municipality) in the Province of Padua in the Italian region Veneto, located about west of Venice and about east of Padua. As of 31 August 2021, it had a population of 7,283 and an area of .
The municipality of Sant'Angelo di Piove di Sacco contains the frazioni (subdivisions, mainly villages and hamlets) Vigorovea and Celeseo.
Sant'Angelo di Piove di Sacco borders the following municipalities: Brugine, Campolongo Maggiore, Fossò, Legnaro, Piove di Sacco, Saonara, Vigonovo.
The airline Alpi Eagles had its head office in Sant'Angelo di Piove di Sacco.