The Sanremo Music Festival 1988 (), officially the 38th Italian Song Festival (), was the 38th annual Sanremo Music Festival, held at the Teatro Ariston in Sanremo between 24 and 27 February 1988 and broadcast by (RAI). The show was presented by Miguel Bosé and Gabriella Carlucci, while hosted the segments from the Sanremo PalaRock, and Kay Sandvick, Lara Saint Paul and Memo Remigi hosted the segments from the Sanremo Casino where a number of foreign guests performed.
The winner of the Big Artists section was Massimo Ranieri with the song "Perdere l'amore", while Fiorella Mannoia won the Critics Award with the song "Le notti di Maggio". The pop group Future won the Newcomers section with the song "Canta con noi".
All shows were broadcast on Rai Uno.
Known details on the broadcasts in each country, including the specific broadcasting stations and commentators are shown in the tables below.