San Pier Niceto (Sicilian: Sanpèri) is a comune (municipality) in the Province of Messina in the Italian region Sicily, located about east of Palermo and about west of Messina. As of 31 December 2004, it had a population of 3,084 and an area of .
The municipality of San Pier Niceto contains the frazioni (subdivisions, mainly villages and hamlets) San Pier Marina, Serro, Zifronte, and Pirrera.
San Pier Niceto borders the following municipalities: Condrò, Fiumedinisi, Gualtieri Sicaminò, Monforte San Giorgio, Pace del Mela, Santa Lucia del Mela.