San Paolo alla Regola, a church in the Regola area of Rome, was made a cardinalate deaconry by Pope Pius XII in 1946. Its present Cardinal-Deacon, since 21 November 2010, is Francesco Monterisi, archpriest emeritus of the Basilica of Saint Paul Outside the Walls.
It is the only church dedicated to Saint Paul within the Walls of Rome.
Underneath Sao Paolo are ruins of what is now a subterranean house.