San Marine is an unincorporated community and census-designated place (CDP) in Lincoln County, Oregon, United States. It was first listed as a CDP prior to the 2020 census. As of the 2020 census, San Marine had a population of 553.
The CDP is in southern Lincoln County, along the Pacific Ocean. U.S. Route 101 passes through the CDP, leading north to Waldport and south to Yachats.