San Giacomo delle Segnate (Lower Mantovano: ) is a comune (municipality) in the Province of Mantua in the Italian region Lombardy, located about southeast of Milan and about southeast of Mantua.
San Giacomo delle Segnate borders the following municipalities: Concordia sulla Secchia, Quistello, and San Giovanni del Dosso.
Villa Arrigona was built between 1619 and 1622 on the commission of Count Pompeo Arrigoni, of the noble Arrigoni family, to the architect Antonio Maria Viani, already in the service of the Gonzagas of Mantua. It is one of the most important villas of the province of Mantua.
The villa, made up of several buildings, was a stately country residence and was usually inhabited seasonally. Built on two floors with an adjoining late Baroque oratory, park and cultivated land. The façade is characterized by a tympanum reminiscent of Palazzo Te, under which the large stone family coat of arms stands out.