The Church of Saint Anthony and Saint Clare () is a Roman Catholic parish church in Montevideo, Uruguay.
This church is part of an important architectural ensemble which includes a convent; it is located on the intersection of the streets Canelones and Minas, in the barrio Palermo. The parish was established on 7 September 1961.
Held by the Friars Minor Capuchin, who have a long history in the territory of Uruguay since colonial times and now conform a Province with Argentina. The church is dedicated to Saint Anthony of Padua and Saint Clare of Assisi.
It boasts a Tamburini organ from 1924, one of the biggest in the country.
There are other churches in Uruguay dedicated to Saint Anthony of Padua: