Salvia graciliramulosa is a shrub that is endemic to the Rio Chico valley of Bolivia, growing in red sandstone outcrops at elevation, often growing in colonies on bare slopes.
S. graciliramulosa has many branches, reaching high, with shortly petiolate leaves that are by . The inflorescence of simple terminal spikes grows up to long, with two-flowered verticillasters and a red to reddish-purple corolla that is long, held in a deep violet calyx.