Salvia cardenasii is a rare and endangered perennial herb that is endemic to Bolivia, found in only three small populations, making it vulnerable to grazing animals and other damage. It grows on grassy slopes near rock outcrops, at approximately elevation.
S. cardenasii grows on dark violet to greenish stems that first lie on the ground, and then grow upright to long. Leaves are oblong to narrowly elliptic, by . The inflorescence is simple terminal racemes with 1âÂÂ4 verticillasters, with a blue corolla that is .