Saltillo is one of the 38 municipalities of Coahuila, in north-eastern Mexico. The municipal seat lies at Saltillo. The municipality covers an area of 6837 km<sup>2</sup>.
As of 2020, the municipality had a total population of 879,958, making it the most populous municipality in Coahuila.
The municipal government is headed by the municipal president of Saltillo (or mayor of Saltillo).