Salt Creek is a tributary of the Little Wabash River, which it joins near Edgewood, Illinois, near the boundary between Effingham and Clay counties. There are at least two other "Salt Creeks" in Illinois: Salt Creek (Des Plaines River tributary) and Salt Creek (Sangamon River tributary).
Salt Creek is about in length.
Salt Creek drains the following cities, towns and villages:
Salt Creek drains parts of the following Illinois counties: