The was a Japanese samurai clan that ruled Mino province in the Sengoku period. The clan appropriated the name of a defunct samurai clan named "Saità Â" that had previously hailed from Echizen province and claimed descent from Fujiwara Toshihito, of the Hokke branch of the Fujiwara clan.
The founder of the Saità  clan was Saità  Dà Âsan (1494âÂÂ1556), who started out as a Buddhist monk, and later worked as a peddler selling cooking oil. In the 1520s, Dà Âsan's father was adopted into the Nagai clan, a minor samurai clan. In 1530, Dà Âsan murdered the head of the Nagai clan and took control. In 1541, Dà Âsan attacked and overthrew the shugo of Mino province, Toki Yorinari. He then adopted the name "Saità Â" from a defunct samurai clan and set himself up as the daimyà  of Mino. For his ruthlessness, Dà Âsan was nicknamed .
Dosan was eventually defeated in 1549 by Oda Nobuhide. Nobuhide made peace with DÃ Âsan by arranging a political marriage between his son and heir, Oda Nobunaga, and DÃ Âsan's daughter, NÃ Âhime. DÃ Âsan, therefore, became the father-in-law of Oda Nobunaga.
Rumors had started to circulate that Dà Âsan's firstborn son, Saità  Yoshitatsu, was not his natural son and Dà Âsan started to consider another son, Kiheiji, or even his son-in-law Oda Nobunaga, as his heirs. This caused Yoshitatsu to rebel and kill his two younger brothers. In 1556, the forces of Dà Âsan and Yoshitatsu clashed in the Battle of Nagara-gawa which resulted in the death of Dà Âsan.
Saità  Tatsuoki was the son of Yoshitatsu. Tatsuoki was defeated by Oda Nobunaga in 1567, and the clan was extinguished.
The Clan Saito and its fictional leader Lord Nariaki Saito from the 2025 action-adventure video game Ghost of Yotei, are loosely based on this clan.